OpenFederal grantOpen to for-profit businessesPAR-25-096

Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

National Institutes of HealthCloses Nov 17, 2026(35 days left)Up to $200,000

Does this fit your business?

This is an NIH/NCI research grant for analyzing existing datasets—clinical, genomic, surveillance, behavioral, environmental—to answer questions about cancer risk, survival, and treatment outcomes. It fits small businesses and other organizations that already have data science or research capability; it is not for companies with no research capacity, and clinical trials are not allowed. The ceiling is $200,000 per award.

Best for
Healthcare and biotech firms with cancer data analysis capability, Universities and research institutions, Nonprofits with research programs, State, local, and tribal government agencies
Not for
Businesses with no research or data analysis capability, Organizations wanting to run clinical trials, Applicants seeking awards above $200,000
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, clinical)
78
Strong Match
Environment & ConservationMatches your industry (environment)
71
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Finance & BankingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
53
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
51
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
48
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, Data analysis
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $200,000

Questions about this grant

When is the application deadline?
Applications are due November 17, 2026.
How much funding can an applicant receive?
The largest award is $200,000, and total program funding is also listed at $200,000.
Who can apply for this grant?
Eligible applicants include small businesses, for-profit organizations other than small businesses, nonprofits with and without 501(c)(3) status, public and private institutions of higher education, independent school districts, state, county, city or township, and special district governments, public housing authorities, and federally recognized or other Native American tribal governments and organizations. Others listed in the eligibility text include HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, tribally controlled colleges, faith-based and community-based organizations, federal agencies, regional organizations, U.S. territories, and foreign
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and for-profit organizations generally, but does not specifically address sole proprietors or single-member LLCs, so it is not published whether they qualify.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH/NCI R21 grants for secondary analysis and integration of existing datasets (clinical, genomic, surveillance, behavioral, environmental) to answer questions about cancer risk, survival, and treatment outcomes. Eligible applicants include small businesses, for-profits, nonprofits, universities, and state/local/tribal governments; clinical trials not allowed. Ceiling $200,000.

About this grant

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Cancer
  • Data science
  • Research

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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