OpenFederal grantRFA-OD-27-009

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

National Institutes of HealthCloses Nov 10, 2026(28 days left)

Does this fit your business?

This is an NIH renewal competition for existing Research Evaluation and Commercialization Hubs that turn academic biomedical discoveries into products. Only universities or research institutions that have already been a formal STTR partner with a small business can apply, so small businesses and for-profits should not bother applying at all. If your organization has never held that STTR partner role, this program is not open to you.

Best for
Universities and research institutions that have already been a formal STTR partner with a small business, Private or public institutions of higher education, Nonprofits with or without 501(c)(3) status that run biomedical commercialization programs
Not for
Small businesses and for-profit companies of any kind, Institutions that have never been a formal STTR partner with a small business, Retail, finance, or real estate organizations
Estimated fit by industry, best first
IndustryEstimated fit
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Agriculture & FarmingLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Construction & InfrastructureLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Finance & BankingLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Food & BeverageLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Healthcare & BiotechLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Housing & Real EstateLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
ManufacturingLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Retail & E-CommerceLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Technology & SoftwareLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring
Transportation & LogisticsLimit: Only governments, nonprofits, tribes or universities may apply —…
0
Worth Exploring

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
R&D, Research, Technical assistance, Training
Who can apply
Colleges and universities, Nonprofits

Questions about this grant

When is the application deadline?
The application deadline is November 10, 2026. The notice was posted on September 24, 2026.
How much funding can an applicant receive?
The facts do not say how much a single award is worth. Total program funding is $5,000,000 with about 5 awards expected, so per-award amounts are not published here.
Who can apply for this grant?
The primary applicant must be a university or other research institution that has been a formal partner to a small business on an NIH STTR award. Eligible organizations are nonprofits with or without 501(c)(3) status (other than institutions of higher education) and private or public/state-controlled institutions of higher education. For-profit businesses and small businesses cannot apply.
Can a sole proprietor or single-member LLC apply?
No. A sole proprietor or single-member LLC cannot apply. The program is open only to universities, research institutions, and nonprofits, and the facts state that for-profit businesses and small businesses are not eligible.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants. However, the primary applicant must still be a university or research institution that has been a formal STTR partner with a small business.

Summary

NIH renewal competition for Research Evaluation and Commercialization Hubs (REACH). Only universities or research institutions that have been formal STTR partners with a small business may apply; nonprofits and higher-ed institutions qualify. Funds create hubs that seed proof-of-concept biomedical projects, mentorship, and entrepreneurship training to translate academic discoveries into products.

About this grant

This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with the funds to seed the creation of academic entrepreneurship Hubs. Hubs will be responsible for providing innovators with both the initial investment and resources to support the proof-of-concept work and the mentorship in product development and commercialization needed to develop high priority technologies within the NIH's mission. Funded Hubs are intended to work as a consortium to enable: (1) the infrastructure for identifying the most promising technologies, (2) funding for product definition studies (e.g. feasibility studies, prototype development, proof-of-concept studies) provided to individual researchers, (3) access to resources and expertise in areas required for early stage technology development (including scientific, regulatory, reimbursement, business, legal, and project management), and (4) skills development and hands-on experience in entrepreneurship. Establishing public-private partnerships and providing additional non-federal funds will be critical for success. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Who can apply

Our reading of the listing: for-profit businesses are not eligible for this one.

The primary applicant organization must be a university or other research institution that participates in the NIH STTR program. Participation means that a university or other research institution has been a formal partner to a small business on an STTR award.

Topics and uses of funds

Topics

  • Health
  • Science
  • Technology

Program contact

National Institutes of Healthnihreach@nih.gov301-402-2541

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