OpenFederal grantOpen to for-profit businessesPAR-27-022

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

National Institutes of HealthCloses Jul 1, 2028(627 days left)$300,000 – $5,000,000

Does this fit your business?

This is an NIH program for groups of NIH-supported investigators who need one expensive, shared piece of research equipment — a single instrument or integrated system costing at least $300,000, with awards up to $5,000,000. If your business has no NIH-funded researchers and no plan to share a major instrument with them, do not bother applying; a retail, finance, or software company will find nothing here. Cost sharing is not required generally, but it is required for premium or special use.

Best for
Groups of NIH-supported investigators at universities and research institutes, Nonprofits with or without 501(c)(3) status running shared research facilities, State, county, city, tribal, and special district governments with research programs, Small businesses and other for-profits sharing a major instrument with NIH-funded investigators
Not for
Businesses with no NIH-funded investigators and no shared research instrument, Foreign organizations or U.S. organizations with foreign components, Organizations seeking general operating funds or routine lab equipment under $300,000
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
81
Strong Match
Education & TrainingMatches your industry (stem)
75
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Equipment
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
$300,000 – $5,000,000

Questions about this grant

When is the application deadline?
July 1, 2028.
How much funding can an applicant receive?
Awards run from $300,000 to $5,000,000. There is no cap on the total cost of the instrument, but the award itself cannot exceed $5,000,000, and cost sharing is required for premium or special use instruments.
Who can apply for this grant?
Groups of NIH-supported investigators at eligible U.S. institutions: public and private higher education, nonprofits with or without 501(c)(3) status, small businesses and other for-profits, state and local governments, tribal governments and organizations, public housing authorities, and independent school districts. Foreign organizations and foreign components of U.S. organizations are not eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and other for-profits, but the NOFO's Section III governs the details, so a sole proprietor or single-member LLC would need to check there.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH Shared Instrumentation Grant Program: groups of NIH-supported investigators at eligible U.S. institutions (universities, nonprofits, governments, tribal organizations, small businesses, and other for-profits) may apply to purchase or upgrade a single shared, state-of-the-art research instrument or integrated instrumentation system costing at least $300,000 in award, up to $5,000,000.

About this grant

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Topics and uses of funds

Topics

  • Science
  • Health
  • Research

Program contact

National Institutes of Healthodsig@mail.nih.gov301-402-2541

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