Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

Does this fit your business?

This is an NIH research grant (R01) for intervention studies aimed at improving Native American health, not a business grant. It fits tribal governments and organizations, Native-serving institutions, and research teams studying health interventions in Native communities. Companies outside that research space, including typical retail, finance, or software businesses with no tribal health research role, should not bother applying.

Best for

Federally recognized tribal governments and tribal organizations, Native-serving nonprofits and community-based organizations, Universities and Native American-serving institutions running health intervention studies, Small businesses partnered with tribes on Native American health research

Not for

Businesses with no tribal partnership or Native American health focus, Foreign entities and non-U.S. organizations, Organizations seeking operating or business development funding rather than research funding

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for

Research

Who can apply

Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?

The application deadline is January 7, 2027.

Who can apply for this grant?

State, local, county, and tribal governments, 501(c)(3) and non-501(c)(3) nonprofits, small and large businesses, public and private universities, independent school districts, housing authorities, and faith- or community-based organizations may apply. Alaska Native, Native Hawaiian, Hispanic-serving, and historically Black institutions, TCCUs, and federal agencies are also eligible. Foreign entities and non-domestic components of U.S. organizations may not apply.

Can a sole proprietor or single-member LLC apply?

The facts do not say. Small businesses are listed as eligible, but the program does not publish whether sole proprietors or single-member LLCs qualify as small businesses for this opportunity.

Can a nonprofit apply?

Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status may apply, as long as they are not institutions of higher education.

Summary

NIH R01 grant for intervention research aimed at improving Native American health. Open to state/local/tribal governments, nonprofits, small and large businesses, universities, school districts, housing authorities, and faith- or community-based organizations; foreign entities may not apply. Funds support health intervention studies.

About this grant

Who can apply

Topics and uses of funds

Program contact