OpenFederal grantOpen to for-profit businessesRFA-DC-27-003

Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)

National Institutes of HealthCloses Aug 21, 2028(678 days left)Up to $500,000

Does this fit your business?

This is an NIH research grant (R01) for developing or adapting non-invasive or minimally invasive imaging technologies to visualize the living human olfactory system. It suits biomedical imaging labs, biotech firms, and multidisciplinary research teams; retail, finance, and real estate businesses have no fit here. Foreign organizations and foreign components of U.S. organizations cannot apply.

Best for
Biotech and medical device developers working on imaging technology, University and academic research teams in biomedical imaging or olfaction, Small businesses in biomedical engineering or diagnostics, Nonprofits and research institutes with imaging science programs
Not for
Retail, finance, or real estate businesses, Companies outside imaging, biotech, or biomedical research, Foreign organizations or U.S. organizations with foreign components
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (medical, biomedical)
94
Strong Match
Technology & SoftwareMatches your industry (tech)
82
Strong Match
Education & TrainingMatches your industry (stem)
72
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
R&D, Research, Equipment
Who can apply
Small businesses, For-profit companies, Nonprofits, Colleges and universities, State and local governments, Tribal governments and organizations, Other applicants (see eligibility)
Award range
Up to $500,000

Questions about this grant

When is the application deadline?
The application deadline is August 21, 2028.
How much funding can an applicant receive?
The largest single award is $500,000, with total program funding of $2,000,000 and about 3 awards expected.
Who can apply for this grant?
Eligible applicants include public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), small businesses, other for-profit organizations, state and local governments, federally recognized tribal governments and tribal organizations, independent school districts, and public housing authorities. Foreign organizations and foreign components of U.S. organizations are not eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list includes small businesses and for-profit organizations, but sole proprietors and single-member LLCs are not specifically named, so check the NOFO's Section III for details.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH (NIDCD/NIBIB) R01 grant to develop or adapt non-invasive/minimally invasive imaging technologies for the living human olfactory system. Eligible applicants include universities, nonprofits, small businesses, other for-profits, state/local/tribal governments, school districts, and housing authorities; foreign entities are excluded.

About this grant

The National Institute on Deafness and Other Communication Disorders (NIDCD), with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) aims to support the development and/or adaptation of transformative in vivo high-resolution/high specificity imaging of the human olfactory system. Currently, there are limited non-invasive/minimally invasive technologies available for imaging the living human peripheral and central olfactory system with high spatial and temporal resolution. Imaging the olfactory system in the laboratory and in the clinic is essential to understanding underlying biological mechanisms as well as the etiology of an olfactory disorder. Such imaging has proven challenging due to the olfactory system"s unique anatomical and functional characteristics such as restricted accessibility, multiple cell types, and low signal resolution. Addressing these challenges requires multimodal approaches including leveraging existing advanced tools and technologies and developing new tools tailored for the olfactory system. Recent advances in minimally invasive and non-invasive imaging technologies, such as cell specific biomarkers, fluorescence imaging, specialized endoscopes, optical and acoustic imaging, molecular imaging, and hemodynamic and diffusion imaging have the potential to transform our ability to image and investigate the peripheral and central olfactory system in the living human with superior temporal and spatial resolution and eventually improve diagnostic accuracy of olfactory disorders. Applications must leverage advanced non-invasive/minimally invasive imaging technologies to visualize peripheral (e.g., olfactory- and non-olfactory epithelium) and central olfactory (e.g., olfactory bulb) targets at a level previously unattainable. In addition, projects should engage multidisciplinary teams combining expertise in olfaction, biomedical imaging, biochemistry, bioengineering, and biophysics, as appropriate.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Topics and uses of funds

Topics

  • Health
  • Science
  • Technology

Program contact

National Institutes of HealthNIDCDOlfactoryImag@mail.nih.gov301-402-2541

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