OpenFederal grantOpen to for-profit businessesPAR-27-069

Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)

National Institutes of HealthCloses Mar 1, 2027(139 days left)

Does this fit your business?

This is an NIH X01 program for researchers who want to run assays on stored plasma, serum, and DNA from the All of Us Biobank and add multiomic data to the All of Us dataset. It is built for biomedical research teams, including small businesses doing genomics, proteomics, or biomarker work. If your business is not doing biomedical research, this is not your grant.

Best for
Biomedical and health researchers at universities and nonprofits, Small biotech and life-science companies running biospecimen or multiomics studies, Government and tribal entities with biomedical research programs
Not for
Businesses outside biomedical research, such as retail, logistics, or finance, Organizations looking for general operating or startup funding, Applicants wanting a straightforward grant with published award amounts
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, medical, clinical)
90
Strong Match
Environment & ConservationMatches your industry (environment)
75
Strong Match
Social Services & NonprofitMatches your industry (community)
66
Good Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureMatches your industry (infrastructure)
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Education & TrainingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Finance & BankingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Food & BeverageLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
53
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
March 1, 2027.
Who can apply for this grant?
Small businesses, other for-profits, nonprofits (with or without 501(c)(3) status), universities, state, local, county, and tribal governments, independent school districts, special district governments, public housing authorities, and other organizations named in the notice. Foreign organizations and foreign components of U.S. organizations may also apply.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and for-profit organizations generally, but the NOFO's Section III is the authority on whether a sole proprietor or single-member LLC qualifies.
Can a nonprofit apply?
Yes. Both 501(c)(3) nonprofits and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH X01 awards let researchers access stored plasma, serum, and DNA from the All of Us Biobank and add new multiomic data to the All of Us dataset. Eligible applicants include small businesses, other for-profits, nonprofits, universities, state/local/tribal governments, school districts, and housing authorities; foreign entities may also apply. Funds support biospecimen assays for precision-medic

About this grant

The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to advance the program's mission of accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.All of Us partnered research studies are collaborative initiatives funded by a study sponsor external to All of Us to collect and add new data to the All of Us Researcher Workbench in accordance with All of Us" best practices. All of Us partnered research studies are open to the broad scientific community and require investigators to apply for and receive an X01 award under this announcement.This will enable longitudinal follow‐up and repeat sampling, and provide multiomic data (genomics, proteomics, metabolomics, and other high‐dimensional molecular profiles), integrated clinical, environmental, and life‐course data, infrastructure designed to support future clinical‐trial recruitment, and public‐private partnership pathways.This opportunity will enable researchers to conduct assays to evaluate associations between newly collected and existing All of Us data and add new data to the All of Us dataset for broad use by the research community. High-priority areas for biospecimen analyses may include, but are not limited to, large scale projects that propose integrated multiomics analyses, early disease detection, biomarker discovery or validation, novel risk models for incident disease, and/or novel disease stratification for chronic disease risk, diagnosis, and prognosis, in support of advancing precision medicine. For more information, please visit the All of Us X01 Partnered Research Studies Resource webpage.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Health
  • Science
  • Biomedical research

Program contact

National Institutes of HealthAoUAncillaryStudies@od.nih.gov301-402-2541

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