ForecastedFederal grantOpen to for-profit businessesPAR-27-049

Ancillary Studies to Ongoing Clinical Projects (RP1 Clinical Trial Not Allowed)

National Institutes of HealthCloses Oct 15, 2026(2 days left)

Does this fit your business?

This NIH program funds ancillary studies bolted onto clinical projects that are already running and funded — trials, observational studies, or disease-specific repositories with existing patients, data, and samples. If you are not already attached to an active parent clinical project, do not bother applying; there is no money here for standalone research or for businesses outside the clinical research space. The award amount is not published.

Best for
Research teams already running an NIH- or otherwise funded clinical trial, observational study, or disease-specific biob, Universities and academic medical centers with active clinical projects, Nonprofits, tribal entities, and community organizations partnered with an ongoing clinical study, Small businesses and for-profits attached to a funded parent project
Not for
Businesses with no connection to an active clinical study, Startups or new projects looking for standalone research funding, Organizations outside healthcare and life sciences research
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
64
Good Match
Education & TrainingMatches your industry (stem)
58
Good Match
Social Services & NonprofitMatches your industry (community)
58
Good Match
Environment & ConservationLimit: Closes in 27 days
54
Possible Match
Technology & SoftwareLimit: Closes in 27 days
50
Possible Match
Arts & CultureLimit: Closes in 27 days
49
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Closes in 27 days
48
Possible Match
Construction & InfrastructureMatches your industry (infrastructure)
47
Possible Match
Housing & Real EstateLimit: Closes in 27 days
47
Possible Match
Agriculture & FarmingLimit: Closes in 27 days
45
Possible Match
Finance & BankingLimit: Closes in 27 days
45
Possible Match
Food & BeverageLimit: Closes in 27 days
44
Possible Match
ManufacturingLimit: Closes in 27 days
43
Possible Match
Retail & E-CommerceLimit: Closes in 27 days
43
Possible Match
Transportation & LogisticsLimit: Closes in 27 days
40
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
October 15, 2026.
Who can apply for this grant?
A wide range: state, county, city, and tribal governments, public and private universities, 501(c)(3) and other nonprofits, small businesses, other for-profit organizations, independent school districts, public housing authorities, federal agencies, U.S. territories, faith-based and community organizations, regional organizations, and foreign institutions.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses and for-profit organizations are eligible, but the notice does not specify whether a sole proprietor or single-member LLC qualifies as an eligible small business under this NOFO.
Can a nonprofit apply?
Yes. Both 501(c)(3) nonprofits and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH funding for time-sensitive ancillary studies attached to active, ongoing clinical projects (trials, observational studies, or disease-specific repositories). Applicants may include governments, universities, nonprofits, small businesses, for-profit organizations, tribal entities, faith-based/community organizations, and foreign institutions. Funds support leveraging existing parent-projectcoh

About this grant

This Notice of Funding Opportunity (NOFO) solicits applications that propose to conduct time-sensitive ancillary studies in conjunction with privately or publicly funded, active, ongoing clinical projects (parent projects). The parent project can be an interventional clinical trial, or a clinical study such as an observational study, or a disease-specific repository that will be actively collecting patient samples or clinical data. The parent project(s) should provide a cohort of well-characterized patients, infrastructure, data, and biological samples for the ancillary study. The objective of this NOFO is to provide a flexible mechanism to leverage currently funded resources and maximize the return on existing investments in parent projects. Successful ancillary studies will enhance the scientific content and value of the parent projects, improve the research community’s understanding of a disease or organ system and thus may identify novel targets for diagnosis, treatment, and prevention of disease.

Who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institute of Arthritis and Musculoskeletal and Skin DiseasesAncillaryStudies@nih.govPlease contact via e-mail.

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