OpenFederal grantOpen to for-profit businessesRFA-OD-27-003

INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

National Institutes of HealthCloses Jun 15, 2028(611 days left)Up to $200,000

Does this fit your business?

This is an NIH research grant for exploratory biomedical, behavioral, or clinical research on Down syndrome, not a business development or general operating grant. It fits research-active organizations including small businesses, universities, and nonprofits. Retail, finance, housing, and any organization without a research or R&D component should not bother applying.

Best for
Biomedical, behavioral, or clinical researchers studying Down syndrome, Universities and research institutions, Small businesses and for-profits with relevant R&D capacity, Nonprofits with a research mission
Not for
Businesses with no research or R&D function, Organizations seeking funding for retail, finance, or housing activities, Projects involving clinical trials
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, medical, biomedical, clinical)
94
Strong Match
Technology & SoftwareMatches your industry (tech)
78
Strong Match
Education & TrainingMatches your industry (stem)
72
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $200,000

Questions about this grant

When is the application deadline?
June 15, 2028.
How much funding can an applicant receive?
The largest single award is $200,000. The total program funding is $1,000,000, with about 5 awards expected.
Who can apply for this grant?
Eligible applicants include independent school districts, federally recognized tribal governments, city or township governments, public housing authorities, county governments, 501(c)(3) nonprofits, state governments, small businesses, special district governments, tribal organizations, for-profit organizations other than small businesses, private and public institutions of higher education, and nonprofits without 501(c)(3) status. Foreign organizations and foreign components of U.S. organizations are also eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not specifically address sole proprietors or single-member LLCs. Small businesses are listed as eligible, but the NOFO's Section III eligibility information should be consulted for details.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are eligible.

Summary

NIH INCLUDE Project R21 awards fund exploratory/developmental biomedical, behavioral, or clinical research on Down syndrome (no clinical trials). Eligible applicants include small businesses, for-profits, nonprofits, universities, state/local/tribal governments, and others; foreign organizations may also apply.

About this grant

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Health
  • Science
  • Research

Program contact

National Institutes of HealthDownSyndromeINCLUDE@mail.nih.gov301-402-2541

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