OpenFederal grantOpen to for-profit businessesPD-26-369Y

Engineering Biological and Biomedical Systems (EBBS)

U.S. National Science FoundationNo deadline listed

Does this fit your business?

This is a National Science Foundation program funding fundamental engineering research on biological and physiological systems: biosensing, tissue engineering, rehabilitation engineering, and biomanufacturing. It is for research-driven organizations, not companies trying to bring a product to market, since commercialization work is pointed elsewhere and clinical trials and drug development are explicitly excluded. If your business is not doing basic biomedical engineering R&D, do not bother.

Best for
Universities and academic labs doing fundamental biomedical engineering research, Small businesses with R&D in biosensing, tissue engineering, rehabilitation engineering, or biomanufacturing, Nonprofits and research institutes running basic science projects on biological systems, Individual researchers studying mechanisms of cells, tissues, or physiological processes
Not for
Companies whose main goal is commercialization, drug design, or drug delivery, Anyone planning clinical trials or therapy testing and validation, Businesses outside biomedical engineering research, such as construction, logistics, or finance
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, medical, biomedical)
82
Strong Match
Technology & SoftwareMatches your industry (technology, tech)
74
Good Match
Education & TrainingMatches your industry (stem)
60
Good Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
ManufacturingMatches your industry (manufacturing)
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Arts & CultureLimit: Nothing in this notice points to arts & culture
50
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
50
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
50
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
49
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
48
Possible Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
47
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
47
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
46
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
45
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, Individuals, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

Who can apply for this grant?
Almost any type of entity can apply: universities and other higher-education institutions, small businesses and other for-profit companies, nonprofits, individuals, government bodies, and tribal entities. The eligible applicant code is listed as Unrestricted. The program funds fundamental engineering research, so the applicant needs a research project, not a commercialization plan.
Can a sole proprietor or single-member LLC apply?
Yes. Small businesses and for-profit companies of any structure are eligible, and the applicant codes are unrestricted, so a sole proprietor or single-member LLC can apply as an individual or for-profit entity. The project still has to be fundamental engineering research on biological or biomedical systems.
Can a nonprofit apply?
Yes. Nonprofits are among the eligible applicant types, and the program is open to any type of entity. The research must fit the program's scope: fundamental engineering research on biological and physiological systems, with no clinical trials or therapy testing.

Summary

NSF Engineering Biological and Biomedical Systems program funds fundamental engineering research on biological and physiological systems—biosensing, tissue engineering, rehabilitation engineering, biomanufacturing. Open to any entity type including universities, small businesses, nonprofits, and individuals; no clinical trials or drug development.

About this grant

The Engineering Biological and Biomedical Systems (EBBS) program expands our understanding of biological and physiological systems, and it helps improve human health. For U.S. leadership in biotechnology, the engineering of biology is required at every scale. Engineering is needed for sensing biomarkers to making proteins to restoring functions of the body. In EBBS, fundamental mechanistic insights are combined with experimental and computational techniques. This approach helps develop platforms, devices, organisms, tissues, and processes that bring new understanding and control of biological functions.

EBBS supports studies of mechanisms that drive the behavior of microbial populations and cells, and of therapeutic cells and tissues. This includes discovering the underlying engineering principles that are needed to capture the responses of biological systems and bioreactors. It also includes the creation of novel biosensing platforms and new optical imaging and modulation strategies. Research that enables the design of biological systems to sense and respond to novel stimuli is welcome. Similarly, projects leading to insight into tissue changes or injury, and to systems that imitate or restore the functions of tissues or organs are encouraged.

Projects that advance rehabilitation engineering through new theories and approaches are supported by the EBBS program. Fundamental engineering research driven by the needs of persons with disabilities is encouraged.

The EBBS program expands what is possible in biomanufacturing; research may advance biotechnology and/or health. EBBS research must enable improved biological processes, create novel biomedical technologies, or achieve new understanding of physiological or pathological processes.

EBBS does not support proposals with a main goal of drug design, drug delivery, or the development of animal models of disease. Using existing models for experimental testing and validation is acceptable. Projects that focus on testing and validating therapies are not supported. Clinical trials are not supported. Limited studies involving human volunteers may be supported if appropriate to the project objectives. Projects focused on commercialization are more appropriate for the NSF Directorate for Technology, Innovation, and Partnerships (TIP).

Partnerships: To speed discovery and innovation, NSF partners with federal agencies, industry, international groups, and others. Current opportunities are at NSF ENG Partnerships.

Who can apply

The listing does not include detailed eligibility text. Check the official listing before you apply.

Topics and uses of funds

Topics

  • Science
  • Health
  • Technology

Program contact

U.S. National Science Foundationgrantsgovsupport@nsf.gov703-292-4203

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