OpenFederal grantOpen to for-profit businessesPAR-25-143

Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

National Institutes of HealthCloses Jan 7, 2028(451 days left)

Does this fit your business?

This is an NIH research grant, not a business subsidy: it funds studies on how evidence-based health interventions get adopted, scaled up, or de-implemented, and it expects research outputs, not commercial products or operating funds. It fits research teams at universities, health systems, nonprofits, governments, and small businesses with genuine health research capability. Retail, finance, housing, and any organization without a health research angle should not bother applying.

Best for
Research teams studying how evidence-based health interventions get adopted, adapted, scaled up, or de-implemented, Universities and academic medical centers running dissemination and implementation research, Nonprofits, tribal organizations, and government agencies with a health research mission, Small businesses and for-profits that can carry out health research within an NIH Institute or Center mission
Not for
Businesses looking for operating capital or commercial funding rather than research support, Organizations outside health research, such as retail, finance, or housing, Applicants needing a specific award amount up front — the funding level is not published
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, clinical)
89
Strong Match
Environment & ConservationMatches your industry (sustainability)
75
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
January 7, 2028.
Who can apply for this grant?
Small businesses, for-profit organizations, nonprofits (with or without 501(c)(3) status), state, county, city, township, and special district governments, public housing and Indian housing authorities, independent school districts, federally recognized and other Native American tribal governments and organizations, and public or private institutions of higher education. Others may also qualify, including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, HBCUs, faith-based and community-based organizations, foreign organizations, and U.S. territories.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are listed as eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify, so check the full announcement before assuming you can apply.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH R21 grants for studies on strategies to adopt, adapt, scale up, or de-implement evidence-based health interventions, practices, and policies, plus advances in dissemination and implementation research methods. Open to small businesses, for-profits, nonprofits, governments, tribes, and universities.

About this grant

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged.All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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