OpenFederal grantOpen to for-profit businessesRFA-NS-27-015

BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

National Institutes of HealthCloses Oct 4, 2027(356 days left)

Does this fit your business?

This is an NIH BRAIN Initiative research grant for teams developing scalable technologies to map brain connectivity in humans, non-human primates, and mice. It is for serious research organizations with neuroscience and technology capabilities, not for businesses looking for general funding. Retail, finance, housing, and construction firms should not bother applying; even the decent construction score just reflects generic timing factors, not any construction focus in the notice.

Best for
Technology and software companies building brain-mapping or data analysis tools, Healthcare and biotech research organizations, Universities and research institutions, Nonprofits with neuroscience research programs
Not for
Retail, e-commerce, finance, or housing businesses, Organizations with no neuroscience or brain research focus, Applicants seeking general business funding or working capital
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
82
Strong Match
Technology & SoftwareMatches your industry (tech)
82
Strong Match
Construction & InfrastructureMatches your industry (construction)
67
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
The application deadline is October 4, 2027.
How much funding can an applicant receive?
The total program funding is $10,000,000. The facts do not state how much an individual applicant can receive, so that amount is not published.
Who can apply for this grant?
Eligible applicants include state, county, city, and special district governments, federally recognized and other Native American tribal organizations, public and private institutions of higher education, independent school districts, public housing authorities, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses. Foreign organizations are also eligible to apply, though foreign components of U.S. organizations are not allowed.
Can a sole proprietor or single-member LLC apply?
The facts do not specifically address sole proprietors or single-member LLCs. Small businesses are listed as eligible, but you should check Section III of the NOFO for details on your specific business structure.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH BRAIN Initiative grants for Specialized Projects developing scalable technologies to map brain connectivity (human, NHP, mouse) and build brain-wide wiring diagrams, including data collection, reconstruction, analysis, and dissemination. Eligible applicants include universities, nonprofits, governments, tribes, and small businesses; foreign entities may apply.

About this grant

This funding announcement, issued by the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative, seeks transformative, cutting-edge, and innovative research that embraces new technologies, ideas, and approaches to understand brain circuit function and contributions to behavior. It is a component of the BRAIN Initiative Connectivity Across Scales (BRAIN CONNECTS) Program, which aims to lay the scientific foundation for the next generation of neural circuit-based approaches for preventing and treating devastating brain disorders.This Notice of Funding Opportunity (NOFO) supports Specialized Projects to develop current or emerging technologies to generate comprehensive atlases of brain connectivity, with an emphasis on human, non-human primate (NHP), and mouse. Projects using other species are also permitted, if their use is well justified and the goal is to test and validate approaches that can be generalized across species. Applications may address any aspect(s) of brain connectivity and associated data pipelines, including data collection, reconstruction, analysis, integration, dissemination, and interpretation, to enable faster, more precise, and more cost-effective generation and interpretation of brain-wide wiring diagrams. Funded projects will be integrated into the BRAIN CONNECTS Network consisting of projects funded under this and preceding BRAIN CONNECTS NOFOs, as a coordinated effort aimed at developing the capabilities to generate wiring diagrams that can span entire brains across multiple scales.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Topics and uses of funds

Topics

  • Science
  • Health
  • Technology

Program contact

National Institutes of HealthBRAIN-CONNECTS-Inquiries@nih.gov301-402-2541

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