OpenFederal grantOpen to for-profit businessesPAR-27-013

Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)

National Institutes of HealthCloses Nov 2, 2028(751 days left)

Does this fit your business?

This is an NIH/NHLBI cooperative agreement to fund a Data Coordinating Center for investigator-initiated multi-site clinical trials, and it only works if you submit alongside a companion Clinical Coordinating Center application (PAR-27-012) on the same due date. It fits organizations that can deliver project coordination, data management, and biostatistics for clinical trials. Retail, finance, and housing businesses with no clinical research capability should not bother.

Best for
Research organizations that can run data management and biostatistics for multi-site clinical trials, Universities and academic medical centers, Nonprofits with clinical research operations, For-profit and small-business CROs or data science firms
Not for
Businesses with no clinical-trial data or biostatistics capability, Applicants planning foreign subawards or subcontracts, Organizations unable to partner on a companion Clinical Coordinating Center application
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
88
Strong Match
Social Services & NonprofitMatches your industry (community)
77
Strong Match
Technology & SoftwareCurrently accepting applications
76
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D, Operating support, Technical assistance
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
November 2, 2028. The notice was posted March 17, 2026.
Who can apply for this grant?
A long list is eligible: small businesses, other for-profits, nonprofits with or without 501(c)(3) status, public and private institutions of higher education, independent school districts, state, county, city or township, special district, and public housing authorities, plus federally recognized tribal governments and other Native American tribal organizations. Foreign organizations and foreign components of U.S. organizations are also eligible, but applications involving foreign subawards or subcontracts will not be considered for funding.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are listed as eligible, but the notice does not spell out how sole proprietors or single-member LLCs are treated, so check Section III of the NOFO or contact NIH before assuming you qualify.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH/NHLBI cooperative agreement to fund a Data Coordinating Center for investigator-initiated multi-site clinical trials (efficacy, comparative effectiveness, pragmatic, implementation). Funds project coordination, administration, data management, and biostatistical support. Eligible applicants include small businesses, for-profits, nonprofits, universities, governments, and tribes; a companion D+

About this grant

This Notice of Funding Opportunity (NOFO) supports applications for a collaborating Data Coordinating Center (DCC) for investigator-initiated multi-site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, and/or prevention strategies. Trials for which this NOFO applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial (see NOT-OD-15-015). For additional information about the mission, strategic vision, and research priorities of the NHLBI, applicants are encouraged to consult the NHLBI website.This NOFO will utilize a milestone-driven cooperative agreement mechanism of award and runs in parallel with a companion NOFO (PAR-27-012) for a collaborating Clinical Coordinating Center (CCC). The objective of the DCC application is to present a comprehensive plan to provide overall project coordination, administration, data management, and biostatistical support for the clinical trial proposed in the collaborating CCC application. The application should also describe its approaches to collaborate with the CCC on implementation of the clinical trial community engagement plan. Both a DCC application and a collaborating CCC application must be submitted on the same application due date for consideration by NHLBI. Applicants are strongly encouraged to contact the appropriate Scientific/Research contact prior to submitting an application.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Topics and uses of funds

Topics

  • Health
  • Science
  • Technology

Program contact

National Institutes of HealthNHLBIDCVSClinical@mail.nih.gov301-402-2541

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