OpenFederal grantOpen to for-profit businessesPAR-25-362

Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)

National Institutes of HealthCloses Nov 5, 2028(754 days left)Up to $400,000

Does this fit your business?

This is an NIH research grant (R01) for studying how the immune system develops before birth and in newborns, infants, children, and teens, including those exposed to HIV or antiretroviral therapy. It is for organizations that can run serious biomedical research, not for businesses looking for general operating funds. If you are in retail, construction, transportation, or any field without a research angle on early immune development, do not bother applying.

Best for
Research labs and universities studying immunology or pediatric health, Small biotech or for-profit research companies, Nonprofits with 501(c)(3) status doing health research, Tribal organizations and government entities with research capacity
Not for
Businesses outside health research, such as retail, construction, or logistics, Organizations without research capability or scientific staff
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
76
Strong Match
Education & TrainingMatches your industry (stem)
70
Good Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Finance & BankingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Food & BeverageLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
53
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
51
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $400,000

Questions about this grant

When is the application deadline?
The application deadline is November 5, 2028.
How much funding can an applicant receive?
The largest award listed is $400,000.
Who can apply for this grant?
Eligible applicants include small businesses, other for-profit organizations, nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, state and local governments, independent school districts, public housing authorities, and Native American tribal governments and organizations. Foreign organizations and certain serving institutions (such as HBCUs and Hispanic-serving institutions) may also apply.
Can a sole proprietor or single-member LLC apply?
The facts do not specifically address sole proprietors or single-member LLCs. For-profit organizations other than small businesses and small businesses are both listed as eligible, so a single-member LLC may qualify, but the notice does not say this explicitly.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH R01 research grants to study early immune system development in utero and in neonates, infants, children and adolescents, including those exposed to HIV or antiretroviral therapy. Eligible applicants include small businesses, other for-profits, nonprofits, universities, governments, and tribal entities; foreign organizations may also apply.

About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune development in utero, during the early post-natal period and during early childhood in neonates, infants, and children and adolescents with or without in-utero exposure to HIV or Anti-Retroviral Therapeutics (ART).This initiative aims to understand intricate mechanisms of immune cells at the maternal-fetal interface, T and B cell development and maturation in offspring, and local immune responses and the role of systemic immunity.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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