OpenFederal grantOpen to for-profit businessesRFA-DA-25-024

High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)

National Institutes of HealthCloses Mar 6, 2027(144 days left)

Does this fit your business?

This is an NIH research grant for studies at the intersection of HIV and substance use, from basic science through clinical and implementation research. It is for organizations that can run a serious research project with preliminary data and a detailed research plan; businesses with no research capability should not bother applying. Individual researchers and teams may apply, and small businesses and for-profits are eligible, but only if the work itself is research.

Best for
Universities and academic research teams, Nonprofits with 501(c)(3) status running HIV or substance use research, State, local, and tribal governments with research programs, Small businesses and for-profits with a research mission
Not for
Businesses with no research capability, Organizations outside the HIV and substance use space
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
78
Strong Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Finance & BankingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Food & BeverageLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
53
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
March 6, 2027.
Who can apply for this grant?
Universities, nonprofits, state and local governments, federally and non-federally recognized tribal organizations, public housing authorities, independent school districts, small businesses, and other for-profit organizations may apply. The eligibility text also lists foreign organizations, faith-based and community-based organizations, and several categories of serving institutions.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses and for-profit organizations are eligible, but the notice does not address sole proprietors or single-member LLCs specifically, so check the full announcement before assuming you qualify.
Can a nonprofit apply?
Yes. Both 501(c)(3) and non-501(c)(3) nonprofits other than institutions of higher education are listed as eligible applicants.

Summary

NIH R01 grants for high-priority research at the intersection of HIV and substance use, from basic science to clinical and implementation studies. Open to universities, nonprofits, governments, tribes, small businesses, and other for-profit organizations; individual researchers and teams may apply.

About this grant

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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