OpenFederal grantOpen to for-profit businessesPAR-26-116

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

National Institutes of HealthCloses Mar 6, 2027(144 days left)Up to $500,000

Does this fit your business?

This is an NIH research grant for collaborative translational research between NIH intramural investigators and outside researchers using NIH Clinical Center resources. It is really for healthcare and biotech research organizations that can partner with NIH scientists; retail, finance, housing, and other businesses with no research or clinical component should not bother applying.

Best for
Healthcare and biotech research organizations, Universities and research institutions, Small businesses doing translational research, Nonprofits with clinical research programs
Not for
Retail and e-commerce businesses, Finance and banking firms, Housing and real estate companies, Organizations without a research focus or NIH collaboration
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, clinical)
89
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $500,000

Questions about this grant

When is the application deadline?
The application deadline is March 6, 2027.
How much funding can an applicant receive?
The largest award listed is $500,000.
Who can apply for this grant?
Eligible applicants include small businesses, for-profit organizations, nonprofits with or without 501(c)(3) status, state and local governments, tribal governments and organizations, public and private institutions of higher education, independent school districts, public housing authorities, and special district governments. Foreign organizations may apply, but foreign subawards are prohibited.
Can a sole proprietor or single-member LLC apply?
The facts do not specifically address sole proprietors or single-member LLCs. Small businesses and for-profit organizations are listed as eligible applicant types, but you should check the NOFO's Section III for details.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH U01 award supporting collaborative translational research between NIH intramural investigators and extramural researchers using NIH Clinical Center resources. Eligible applicants include small businesses, for-profit organizations, nonprofits, universities, state/local/tribal governments, and others; foreign organizations may apply but foreign subawards are prohibited.

About this grant

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of HealthClinicalCtrPartner@mail.nih.gov301-402-2541

Open opportunities funding similar work, from the same funder or in the same place.