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OpenFederal SBIR/STTROpen to for-profit businessesARPA-H 01

Development of an annual test to inform women about their future fertility

Department of Health and Human Services, ARPA-HCloses Sep 30, 2027(345 days left)

Does this fit your business?

This is an ARPA-H SBIR/STTR topic for US for-profit small businesses (500 or fewer employees, majority US-owned) doing R&D on an affordable annual diagnostic test that assesses women's fertility status and estimates the timeline to infertility. It funds research, not operations or general business costs. Nonprofits and businesses outside diagnostics, biotech, or health technology should not bother applying.

Best for
US for-profit small businesses with 500 or fewer employees, Diagnostics and biotech developers working on fertility or women's health tests, Health technology companies building patient-facing monitoring tools, Small businesses partnering with a nonprofit research institution under STTR
Not for
Nonprofit organizations, Businesses with more than 500 employees or majority foreign ownership, Companies outside health, diagnostics, or related technology R&D
Estimated fit by industry, best first
IndustryEstimated fit
Technology & SoftwareMatches your industry (sbir, sttr)
57
Good Match
Healthcare & BiotechMatches your industry (health)
50
Possible Match
Energy & Clean TechLimit: Primarily for minority-owned businesses
39
Possible Match
Housing & Real EstateMatches your industry (affordable)
37
Possible Match
Agriculture & FarmingLimit: Primarily for minority-owned businesses
32
Worth Exploring
Food & BeverageLimit: Primarily for minority-owned businesses
30
Worth Exploring
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Finance & BankingLimit: Primarily for minority-owned businesses
29
Worth Exploring
ManufacturingLimit: Primarily for minority-owned businesses
29
Worth Exploring
Retail & E-CommerceLimit: Primarily for minority-owned businesses
27
Worth Exploring
Transportation & LogisticsLimit: Primarily for minority-owned businesses
26
Worth Exploring
Construction & InfrastructureLimit: Primarily for minority-owned businesses
25
Worth Exploring
Arts & CultureLimit: This program does not accept nonprofit applicants.
0
Worth Exploring
Education & TrainingLimit: This program does not accept nonprofit applicants.
0
Worth Exploring
Environment & ConservationLimit: This program does not accept nonprofit applicants.
0
Worth Exploring
Social Services & NonprofitLimit: This program does not accept nonprofit applicants.
0
Worth Exploring

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
R&D, Research
Who can apply
Small businesses

Questions about this grant

When is the application deadline?
Proposals are accepted starting June 11, 2026 and close September 30, 2027. Check the official solicitation for the exact due time.
Who can apply for this grant?
For-profit US small businesses with 500 or fewer employees, including affiliates, that are more than 50% owned and controlled by US citizens or permanent residents. Under SBIR the principal investigator must be primarily employed by the business; under STTR the business partners with a US nonprofit research institution or university that does at least 30% of the work. The business must be registered in SAM.gov before submitting.
Can a sole proprietor or single-member LLC apply?
The facts state applicants must be for-profit US businesses with 500 or fewer employees, but they do not say whether sole proprietors or single-member LLCs specifically qualify. Check the official solicitation.
Can a nonprofit apply?
No. Only for-profit small businesses may apply. Under the STTR track a nonprofit research institution can be a partner, but it cannot be the applicant.

Summary

SBIR/STTR Phase I and II funding for US small businesses (≤500 employees, majority US-owned) to develop an affordable annual diagnostic test that assesses women's fertility status and estimates the timeline to infertility, using new biomarkers to support fertility planning and women's health monitoring tools.

About this grant

Development of an annual test to inform women about their future fertility - The purpose of this topic is to discover new biomarkers that provide women with actionable data for fertility planning.  Results from this work will help inform the program manager regarding the feasibility of future programs focused on enhancing natural fertility before the need of IVF and guiding the development of women’s health monitoring and improvement tools. This work will develop a diagnostic test that can assess fertility status and generate an estimated timeline for the onset of infertility. This topic seeks to develop a test that is affordable, suitable for at least annual use, and provides user-friendly results for patients and care teams to support childbearing decisions.

Program: SBIR/STTR, Phase I and Phase II Agency: Department of Health and Human Services, ARPA-H Topic number: ARPA-H 01 Solicitation: 7599226SN106 Proposals accepted from June 11, 2026 Closes September 30, 2027. Check the official solicitation for the exact due time. Official solicitation: https://sam.gov/workspace/contract/opp/34fa75da1d484987bd6dbc882deab889/view Listed on SBIR.gov: https://www.sbir.gov/topics/12786. SBIR.gov copies agency solicitations and can lag behind them; the official solicitation is the final word.

Who can apply

Small businesses only: a for-profit US business with 500 or fewer employees, including affiliates.

More than 50% owned and controlled by US citizens or permanent residents (some agencies also accept majority ownership by venture capital, hedge fund or private equity firms; the solicitation says).

SBIR: the principal investigator is primarily employed by the business. STTR: the business partners with a US nonprofit research institution or university, which does at least 30% of the work.

Registered in SAM.gov before submitting.

Check the official solicitation for its own conditions, proposal limits and security review.

Topics and uses of funds

Topics

  • Health
  • Technology
  • Science

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