This is an ARPA-H SBIR/STTR topic for US for-profit small businesses with 500 or fewer employees to build a high-resolution, anatomically accurate virtual human brain as a first step toward AI-assisted neurosurgical robotics. It is for R&D-stage technology or healthcare/biotech firms; companies outside that research space, and nonprofits entirely, should not bother applying.
| Industry | Estimated fit |
|---|---|
| Technology & SoftwareMatches your industry (sbir, sttr) | 82 |
| Healthcare & BiotechMatches your industry (health) | 75 |
| Energy & Clean TechLimit: Primarily for minority-owned businesses | 54 |
| Finance & BankingLimit: Primarily for minority-owned businesses | 54 |
| Food & BeverageLimit: Primarily for minority-owned businesses | 54 |
| Housing & Real EstateLimit: Primarily for minority-owned businesses | 54 |
| Industry | Estimated fit |
|---|---|
| ManufacturingLimit: Primarily for minority-owned businesses | 54 |
| Retail & E-CommerceLimit: Primarily for minority-owned businesses | 54 |
| Construction & InfrastructureLimit: Primarily for minority-owned businesses | 53 |
| Agriculture & FarmingLimit: Primarily for minority-owned businesses | 52 |
| Transportation & LogisticsLimit: Primarily for minority-owned businesses | 52 |
| Arts & CultureLimit: This program does not accept nonprofit applicants. | 0 |
| Education & TrainingLimit: This program does not accept nonprofit applicants. | 0 |
| Environment & ConservationLimit: This program does not accept nonprofit applicants. | 0 |
| Social Services & NonprofitLimit: This program does not accept nonprofit applicants. | 0 |
These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.
SBIR/STTR Phase I and II topic for US small businesses (≤500 employees, majority US-owned) to develop a high-resolution, physically and anatomically accurate virtual human brain as a first step toward AI-assisted intracranial microsurgery and neurosurgical robotics. STTR requires a nonprofit research partner doing ≥30% of the work.
The purpose of this topic aims to take a first step toward AI-assisted intracranial microsurgery by creating a high-resolution, physically and anatomically accurate virtual human brain.
Program: SBIR/STTR, Phase I and Phase II Agency: Department of Health and Human Services, ARPA-H Topic number: ARPA-H 07 Solicitation: 7599226SN106 Proposals accepted from June 11, 2026 Closes September 30, 2027. Check the official solicitation for the exact due time. Official solicitation: https://sam.gov/workspace/contract/opp/34fa75da1d484987bd6dbc882deab889/view Listed on SBIR.gov: https://www.sbir.gov/topics/12792. SBIR.gov copies agency solicitations and can lag behind them; the official solicitation is the final word.
Small businesses only: a for-profit US business with 500 or fewer employees, including affiliates.
More than 50% owned and controlled by US citizens or permanent residents (some agencies also accept majority ownership by venture capital, hedge fund or private equity firms; the solicitation says).
SBIR: the principal investigator is primarily employed by the business. STTR: the business partners with a US nonprofit research institution or university, which does at least 30% of the work.
Registered in SAM.gov before submitting.
Check the official solicitation for its own conditions, proposal limits and security review.
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