This is an ARPA-H SBIR/STTR topic funding US small businesses developing bioadhesives that seal, bond, and repair tissue in wet, bloody, or dynamic surgical environments. It is for for-profit companies with 500 or fewer employees doing serious R&D; nonprofits and businesses outside biotech, medical devices, or health technology should not bother applying.
| Industry | Estimated fit |
|---|---|
| Technology & SoftwareMatches your industry (sbir, sttr) | 82 |
| Healthcare & BiotechMatches your industry (health, clinical) | 79 |
| Agriculture & FarmingLimit: Primarily for minority-owned businesses | 54 |
| Energy & Clean TechLimit: Primarily for minority-owned businesses | 54 |
| Food & BeverageLimit: Primarily for minority-owned businesses | 54 |
| Housing & Real EstateLimit: Primarily for minority-owned businesses | 54 |
| Industry | Estimated fit |
|---|---|
| Construction & InfrastructureLimit: Primarily for minority-owned businesses | 53 |
| Retail & E-CommerceLimit: Primarily for minority-owned businesses | 53 |
| Transportation & LogisticsLimit: Primarily for minority-owned businesses | 53 |
| Finance & BankingLimit: Primarily for minority-owned businesses | 52 |
| ManufacturingLimit: Primarily for minority-owned businesses | 52 |
| Arts & CultureLimit: This program does not accept nonprofit applicants. | 0 |
| Education & TrainingLimit: This program does not accept nonprofit applicants. | 0 |
| Environment & ConservationLimit: This program does not accept nonprofit applicants. | 0 |
| Social Services & NonprofitLimit: This program does not accept nonprofit applicants. | 0 |
These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.
SBIR/STTR Phase I and II funding for US small businesses (500 or fewer employees) to develop next-generation bioadhesive platforms that seal, bond, and repair tissues in wet, bloody, and dynamic clinical environments, including drug/biologic delivery. SBIR requires the PI be primarily employed by the business; STTR requires partnership with a US nonprofit research institution.
The purpose of this topic is to develop next-generation bioadhesive platforms that can safely and reliably seal, bond, and repair a wide range of tissues in challenging clinical conditions, including wet, bloody, and mechanically dynamic environments. These platforms may also be designed to deliver biologics or small molecules as part of treatment. The goal is to create bioadhesives with key performance attributes such as strong tissue adhesion, controlled degradation, reversibility, biocompatibility, and broad compatibility across multiple tissues and organs. If successful, this topic could enable widely deployable solutions for hemostasis, leak prevention, tissue repair, and device fixation, ultimately helping reduce complications and improve patient outcomes across many care settings.
Program: SBIR/STTR, Phase I and Phase II Agency: Department of Health and Human Services, ARPA-H Topic number: ARPA-H 02 Solicitation: 7599226SN106 Proposals accepted from June 11, 2026 Closes September 30, 2027. Check the official solicitation for the exact due time. Official solicitation: https://sam.gov/workspace/contract/opp/34fa75da1d484987bd6dbc882deab889/view Listed on SBIR.gov: https://www.sbir.gov/topics/12787. SBIR.gov copies agency solicitations and can lag behind them; the official solicitation is the final word.
Small businesses only: a for-profit US business with 500 or fewer employees, including affiliates.
More than 50% owned and controlled by US citizens or permanent residents (some agencies also accept majority ownership by venture capital, hedge fund or private equity firms; the solicitation says).
SBIR: the principal investigator is primarily employed by the business. STTR: the business partners with a US nonprofit research institution or university, which does at least 30% of the work.
Registered in SAM.gov before submitting.
Check the official solicitation for its own conditions, proposal limits and security review.
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