OpenFederal grantOpen to for-profit businessesRFA-DA-27-004

BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

National Institutes of HealthCloses Nov 8, 2027(391 days left)

Does this fit your business?

This is an NIH BRAIN Initiative research grant for teams building computational theories, models, and analysis methods for brain data, meant to be shared with the wider research community. It fits research-driven organizations, not businesses selling products or services. If you are not doing or partnering on serious computational neuroscience R&D, do not apply.

Best for
Universities and research institutions, Nonprofits with neuroscience or computational research programs, Small businesses and for-profits doing brain-data R&D, State, local, and tribal government research offices
Not for
Retail, finance, or real estate businesses with no research angle, Organizations wanting funding for operations, equipment, or services rather than research, Applicants planning clinical trials
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
82
Strong Match
Technology & SoftwareCurrently accepting applications
75
Strong Match
Education & TrainingMatches your industry (stem)
74
Good Match
Social Services & NonprofitMatches your industry (community)
70
Good Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Construction & InfrastructureMatches your industry (building)
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D, Technical assistance
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
November 8, 2027.
Who can apply for this grant?
Universities (public, state-controlled, and private), independent school districts, nonprofits with or without 501(c)(3) status, small businesses and other for-profit organizations, state/county/city/tribal and special district governments, public housing authorities, and certain other entities including federal agencies, faith- and community-based organizations, regional organizations, and foreign (non-U.S.) entities.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses and for-profit organizations generally are listed as eligible, but sole proprietors and single-member LLCs are not named specifically, so check the full notice or ask NIH program staff before counting on it.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH BRAIN Initiative R01 grants to develop and disseminate computational theories, models, and analysis methods for understanding brain circuits and function. Eligible applicants include universities, nonprofits, state/local/tribal governments, federal agencies, faith- and community-based organizations, foreign entities, and both small businesses and other for-profit organizations. Clinical trials

About this grant

The Theories, Models and Methods (TMM) initiative will support the development of computational tools for understanding dynamic brain circuits that are made broadly accessible to the greater research community. This program supports applications focused on tool building and dissemination in the domain of theories about neural circuit mechanisms, models of circuit structure and function, and/or computational methods of analysis spanning across scales from neurons to behavior. The development of novel theories, computational models and methods for understanding brain function will help characterize fundamental principles of brain function and organization, characterize cellular and circuit-level neural computations over time in different regions, and understand how interactions of multiple brain circuits enable flexible behaviors and contribute to brain-wide neural dynamics. These tools will be critical for developing treatments such as closed loop systems for brain disorders including Parkinsons disease and major depressive disorder.

Who can apply

Other Eligible Applicants include the following:

Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Science
  • Health
  • Technology

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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