OpenFederal grantOpen to for-profit businessesPAR-25-322

Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

National Institutes of HealthCloses Aug 25, 2028(682 days left)

Does this fit your business?

This is an NIH R01 grant for early stage investigators in biomedical research whose project is a change in research direction with no preliminary data. It fits research-active organizations like universities, hospitals, nonprofits, and small businesses in healthcare and biotech. If you are not doing biomedical research, or you need funding for a product, service, or expansion, do not apply.

Best for
Early stage investigators in biomedical research, Universities, hospitals, and research nonprofits, Small businesses with a research program, US-based organizations only
Not for
Businesses outside healthcare and biotech, Foreign or non-US-based organizations, Researchers with preliminary data or established research programs
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
81
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Transportation & LogisticsLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
The deadline is August 25, 2028.
Who can apply for this grant?
US-based organizations can apply, including small businesses, for-profit companies other than small businesses, nonprofits (with or without 501(c)(3) status), state, county, city, and tribal governments, public housing authorities, independent school districts, and public, private, and state-controlled institutions of higher education. Foreign entities, non-US components of US organizations, and foreign components are not eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are listed as eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status, other than institutions of higher education, are both listed as eligible applicants.

Summary

NIH R01 grant for early stage investigators (typically at universities, hospitals, nonprofits, or small businesses) pursuing an innovative, preliminary-data-free change in research direction in biomedical science. US-based organizations only; foreign entities ineligible.

About this grant

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Topics and uses of funds

Topics

  • Health
  • Science
  • Research

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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