OpenFederal grantOpen to for-profit businessesPAR-27-003

Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

National Institutes of HealthCloses Sep 26, 2029(1077 days left)

Does this fit your business?

This is an NIH research grant for highly integrated multidisciplinary teams pursuing one ambitious, focused research project that no single investigator could tackle alone. It fits research-heavy organizations in healthcare, biotech, and adjacent sciences; it does not fit solo operators, ordinary small businesses without a genuine research team, or companies in retail, transportation, or manufacturing looking for general business funding.

Best for
Multidisciplinary research teams at universities and medical centers, NIH-funded investigators with complementary expertise tackling one ambitious project, Nonprofits and research institutes running health or biomedical science programs, Small businesses and for-profits with serious R&D capability in health-related science
Not for
Solo founders or single-investigator projects without a multidisciplinary team, Businesses outside research and R&D, such as retail, transportation, or manufacturing operations, Organizations looking for general operating or commercialization funding rather than research support
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechDeadline is more than 60 days away
66
Good Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
52
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
52
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
52
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
48
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
48
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
47
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
47
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
44
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
The application deadline is January 26, 2027.
Who can apply for this grant?
Eligible applicants include state, county, city, and tribal governments, public and private institutions of higher education, independent school districts, public housing authorities, nonprofits with or without 501(c)(3) status, small businesses, other for-profit organizations, federally recognized tribal organizations, and certain other entities such as federal agencies, U.S. territories, faith-based or community-based organizations, and regional organizations.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify, so check the full opportunity listing (PAR-27-003) before assuming you can apply.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH program grant funding highly integrated multidisciplinary teams of investigators pursuing ambitious, focused research projects requiring synergistic collaboration. Open to universities, nonprofits, governments, tribes, small businesses, and other for-profit organizations.

About this grant

This Notice of Funding Opportunity (NOFO) supports interdisciplinary research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions. Collaborative program teams are expected to be integrated, working together to tackle a single focused scientific goal that requires considerable synergy and meaningful team interaction. Program goals should not be achievable through individual efforts or a collection of projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityForeign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Topics and uses of funds

Topics

  • Science
  • Health
  • Research

Program contact

National Institutes of HealthNIGMS-TeamScience@NIH.gov301-402-2541

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