Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)

Does this fit your business?

This is an NIH/NCI research grant (R01) for teams that pair academic researchers with industry partners to translate in vivo imaging, data science, or spectroscopic technologies into tools for cancer and other disease research, diagnosis, or treatment. If you are a small biotech, medtech, or research-driven company with an academic collaborator, it is worth a look. If you run a retail, finance, or general services business with no imaging or health research angle, do not bother applying.

Best for

Small biotech or medical-device companies with imaging or spectroscopy technology, Academic labs and universities working on cancer or disease imaging, Nonprofits with research capacity in health technology, Teams that can form an academic-industrial partnership

Not for

Retail, e-commerce, finance, or real estate businesses with no imaging or health research angle, Companies without a research or academic partner, Businesses seeking working capital or general operating funds

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for

R&D, Research

Who can apply

Small businesses, For-profit companies, Nonprofits, Colleges and universities, State and local governments, Tribal governments and organizations, Other applicants (see eligibility)

Award range

Up to $500,000

Questions about this grant

When is the application deadline?

January 7, 2027.

How much funding can an applicant receive?

The largest award is $500,000, and total program funding is $500,000. No cost sharing is required.

Who can apply for this grant?

Small businesses, for-profit companies, nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, independent school districts, state, county, city and tribal governments, public housing authorities, and special district governments can apply. Foreign organizations, faith-based and community-based organizations, and certain serving institutions such as HBCUs and Hispanic-serving institutions are also eligible.

Can a sole proprietor or single-member LLC apply?

The facts do not say. Small businesses are eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify, so check the full notice on Grants.gov (opportunity PAR-25-079) before assuming you can apply.

Can a nonprofit apply?

Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH/NCI R01 grants for academic-industrial partnerships to translate and validate in vivo imaging, data science, and spectroscopic technologies for cancer and other disease research, diagnosis, and treatment. Eligible applicants include small businesses, for-profits, nonprofits, universities, and governments.

About this grant

Who can apply

Topics and uses of funds

Program contact