OpenFederal grantOpen to for-profit businessesRFA-MH-26-120

BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)

National Institutes of HealthCloses Jun 15, 2027(245 days left)

Does this fit your business?

This is an NIH BRAIN Initiative program to build facilities at minority-serving and IDeA-eligible institutions that manufacture and distribute brain cell type-specific reagents like viral vectors, nucleic acid constructs, and nanoparticles to neuroscientists. It fits small biotech or life-science businesses that can run scaled production and distribution of these reagents. Retail, finance, or real estate businesses with no lab or production capability should not bother applying.

Best for
Small biotech or life-science businesses that can run scaled production of viral vectors, nucleic acid constructs, ornan
Not for
Retail, finance, or real estate businesses with no lab or production capability, Foreign organizations or companies with non-U.S. components, Businesses looking for general operating capital or startup funding unrelated to neuroscience reagents
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
80
Strong Match
Technology & SoftwareMatches your industry (tech)
78
Strong Match
Social Services & NonprofitMatches your industry (community)
76
Strong Match
ManufacturingMatches your industry (production)
72
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Infrastructure, Equipment, Operating support
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
June 15, 2027.
Who can apply for this grant?
Small businesses, for-profit organizations, nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, state/local/tribal governments, public housing authorities, independent school districts, and special district governments. Foreign organizations are not eligible, and non-domestic components of U.S. organizations cannot apply.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility codes list small businesses and for-profit organizations other than small businesses, but the notice does not spell out how sole proprietors or single-member LLCs are treated, so check the full NOFO or ask the NIH program contact.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH BRAIN Initiative funding to establish facilities at minority-serving institutions and IDeA-eligible institutions for scaled production and distribution of brain cell type-specific reagents (viral vectors, nucleic acid constructs, nanoparticles) for the neuroscience research community. Eligible applicants include small businesses, for-profits, nonprofits, universities, and governments.

About this grant

This Notice of Funding Opportunity Announcement (NOFO) from the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is intended to support establishment of facilities at minority-serving institutions (MSIs) and Institutional Development Award (IDeA)-eligible institutions for scaled production and distribution of brain cell type-specific access and manipulation reagents. Reagents will be initially developed in pilot resource projects for brain cell type-specific access and manipulation across vertebrate species from the BRAIN Initiative Armamentarium project. Awardees under this NOFO will work with the other Armamentarium awardees to manufacture and distribute the resources for use throughout the neuroscience community. It is envisioned that the awardees will work both with the Armamentarium community as well as with the neuroscience research community to optimize the use of new reagents. The types of reagents to be produced and distributed could include but are not limited to viral vectors, nucleic acid constructs, and nanoparticles designed for selective access to and manipulation of brain cell types. Such reagents will enable neuroscientists to probe circuit function with high precision in experimental animals and ex vivo human tissue and cells. Facilities are needed to contribute to the production and distribution of BRAIN Initiative Armamentarium project reagents broadly to neuroscience users.

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Science
  • Health
  • Technology

Set-asides

  • Minority serving institutions

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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