OpenFederal grantOpen to for-profit businessesPAR-25-311

Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)

National Institutes of HealthCloses Nov 15, 2027(398 days left)Up to $6,250,000

Does this fit your business?

This is an NIH/NICHD research program, not a business grant: it funds multisite clinical trials and observational studies on infants, children, women, pregnant and lactating women, and persons with disabilities, run through NICHD clinical research networks. It fits research-capable organizations that can partner with a NICHD Network Data Coordinating Center. Retail, finance, housing, and other businesses with no clinical research role should not bother applying.

Best for
Healthcare and biotech research teams running multisite clinical trials or observational studies in NICHD network areas, Universities and academic medical centers, Nonprofits with research capacity, Small businesses doing clinical research in these populations
Not for
Retail, finance, housing, and other businesses with no clinical research role, Organizations that cannot partner with a NICHD Network Data Coordinating Center, Foreign entities
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
78
Strong Match
Social Services & NonprofitMatches your industry (community)
75
Strong Match
Transportation & LogisticsMatches your industry (transit)
67
Good Match
Construction & InfrastructureMatches your industry (infrastructure)
66
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, Clinical trials, Operating support
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $6,250,000

Questions about this grant

When is the application deadline?
The application deadline is November 15, 2027.
How much funding can an applicant receive?
The largest award is $6,250,000. No other award amounts are published in the notice.
Who can apply for this grant?
Eligible applicants include small businesses, other for-profit organizations, nonprofits (with or without 501(c)(3) status), private and public institutions of higher education, state, county, city, township, and special district governments, federally recognized tribal governments and other tribal organizations, public and Indian housing authorities, and independent school districts. Foreign entities are not eligible.
Can a sole proprietor or single-member LLC apply?
The notice does not specifically address sole proprietors or single-member LLCs. Small businesses and other for-profit organizations are listed as eligible, but the facts do not say whether a sole proprietorship or single-member LLC qualifies.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH/NICHD program funding multisite, investigator-initiated clinical trials and observational studies using NICHD clinical research networks focused on infants, children, women, pregnant and lactating women, and persons with disabilities. Eligible applicants include small businesses, other for-profits, nonprofits, universities, tribal entities, and governments; foreign entities are excluded.

About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating women, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. This NOFO will utilize a bi-phasic (UG3/UH3), milestone-driven mechanism consisting of a start-up phase (UG3) and a full enrollment and clinical trial implementation phase (UH3). Applications submitted in response to this NOFO must address specific aims and milestones for both the UG3 and UH3 phases. A UG3 project (phase I) that meets its milestones will be administratively considered by NICHD and prioritized for transition to the UH3 award (phase II). This NOFO provides an opportunity to leverage NICHD clinical research Network infrastructure as a platform for investigator-initiated innovative hypotheses by any investigator in the extramural community. Applications must be submitted as investigator-initiated, multi-Project Director/Principal Investigator (PD/PI) grant applications in conjunction with the respective NICHD-supported Network Data Coordinating Center (DCC), or equivalent as determined by the NICHD.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Topics and uses of funds

Topics

  • Health
  • Research
  • Children
  • Women
  • Disability

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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