OpenFederal grantOpen to for-profit businessesPAR-25-091

Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

National Institutes of HealthCloses Jan 7, 2028(451 days left)Up to $75,000

Does this fit your business?

This is an NIH small research grant (R03, up to $75,000) for researchers who already hold an NIDDK K01, K08, K23, or K25 career development award and are finishing their transition to independent investigator status. It funds short pilot studies, secondary data analysis, and methodology work that produce preliminary data for a future R01 application. If you do not currently hold one of those NIDDK K awards, do not bother applying; no amount of business fit changes that.

Best for
Current NIDDK K01, K08, K23, or K25 awardees transitioning to independent investigator status, Healthcare and biotech researchers running short-term pilot or feasibility studies, Small businesses and nonprofits that can host a researcher's preliminary-data project, Higher education institutions supporting faculty moving toward R01 applications
Not for
Small-business owners without a current NIDDK K01/K08/K23/K25 award, Retail, finance, housing, or other businesses outside health research, Organizations seeking general operating or business expansion funding
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
79
Strong Match
Technology & SoftwareMatches your industry (technology, tech)
79
Strong Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Education & TrainingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsMatches your industry (transit)
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $75,000

Questions about this grant

When is the application deadline?
January 7, 2028. The notice was posted January 9, 2025.
How much funding can an applicant receive?
The largest award is $75,000. No other award amounts are published.
Who can apply for this grant?
Current NIDDK K01, K08, K23, or K25 career-award recipients in the latter years of their K award who are transitioning to fully independent investigator status. Eligible organizations include small businesses, for-profits, nonprofits, governments, tribes, and higher education institutions, but the K-award requirement is the real gate. Foreign organizations and non-domestic components of U.S. organizations are not eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility text lists small businesses and for-profit organizations among eligible applicants, but it does not address sole proprietors or single-member LLCs specifically, and the K-award recipient requirement applies regardless of business structure.
Can a nonprofit apply?
Yes. Nonprofits with or without 501(c)(3) status (other than institutions of higher education) are listed as eligible, though the applicant must still be a current NIDDK K01/K08/K23/K25 recipient.

Summary

NIDDK small grants (R03) for current NIDDK K01/K08/K23/K25 career-award recipients transitioning to independent investigator status. Funds short-term pilot/feasibility studies, secondary data analysis, small self-contained projects, and research methodology/technology development that generate preliminary data for future R01 applications.

About this grant

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) announces a program that provides NIDDK-supported K01, K08, K23, and K25 recipients the opportunity to apply for Small Grant (R03) support at some point during the latter years of their award period of their K award. Through the use of this mechanism, the NIDDK is seeking to enhance the capability of its K01, K08, K23, and K25 award recipients to conduct research as they complete their transition to fully independent investigator status. The R03 grant mechanism supports different types of projects, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that may provide preliminary data to support a subsequent R01, or equivalent, application.

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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