OpenFederal grantOpen to for-profit businessesPA-25-302

NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

National Institutes of HealthCloses Jan 7, 2028(451 days left)Up to $50,000

Does this fit your business?

This is an NIH program for small, short-duration health and science research projects such as pilot studies, secondary data analysis, and research methodology or technology development, with awards up to $50,000. It fits small businesses, for-profits, nonprofits, universities, and governments that actually do research. If you are not running a research project, or you need working capital or general operating money, do not apply; clinical trials are not allowed.

Best for
Small businesses and for-profits doing health or science R&D, Universities and higher-ed institutions, Nonprofits with research capacity, State, local, and tribal governments running research projects
Not for
Businesses wanting working capital or general operating funds, Organizations planning clinical trials, Retail, finance, or real estate businesses with no research component
Estimated fit by industry, best first
IndustryEstimated fit
Technology & SoftwareMatches your industry (technology, tech)
93
Strong Match
Healthcare & BiotechMatches your industry (clinical)
90
Strong Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $50,000

Questions about this grant

When is the application deadline?
The application deadline is January 7, 2028.
How much funding can an applicant receive?
The largest award is $50,000.
Who can apply for this grant?
Eligible applicants include small businesses, for-profit organizations, nonprofits (with and without 501(c)(3) status), public and private institutions of higher education, independent school districts, state, county, city, and special district governments, federally recognized tribal governments, Native American tribal organizations, and public housing authorities. Other eligible applicants include HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, AANAPISISs, tribally controlled colleges and universities, faith-based and community-based organizations, regional organizations, federal agencies, U.S. territories, and some foreign (non-U.S.) entities.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify as small businesses for this program.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH small research grants (R03) up to $50,000 for short pilot/feasibility studies, secondary data analysis, methodology and new research technology development. Eligible: small businesses, for-profits, nonprofits, universities, state/local/tribal governments, faith- and community-based orgs, and some foreign entities. Clinical trials not allowed.

About this grant

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Science
  • Research

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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