OpenFederal grantOpen to for-profit businessesPAR-25-175

Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)

National Institutes of HealthCloses Jan 7, 2028(451 days left)Up to $500,000

Does this fit your business?

This is an NIH/NCI R01 research grant for projects that combine imaging and liquid biopsy tumor monitoring during cancer therapy to measure treatment response and resistance. It is for organizations that can run patient-based clinical research, such as universities, hospitals, nonprofits, and small biotech businesses. Retail, construction, transportation, and other businesses with no cancer research capability should not bother applying.

Best for
Universities and academic cancer research centers, Hospitals and nonprofit research organizations, Small biotech or diagnostics companies with clinical research capability, State, local, and tribal government research programs
Not for
Businesses with no clinical research or cancer diagnostics capability, Foreign organizations or U.S. organizations with foreign components, Organizations looking for funding for anything other than research
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
75
Strong Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Education & TrainingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Finance & BankingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Food & BeverageLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Technology & SoftwareLimit: Nothing in this notice points to technology & software
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
53
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
53
Possible Match
Transportation & LogisticsLimit: Nothing in this notice points to transportation & logistics
53
Possible Match
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
51
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)
Award range
Up to $500,000

Questions about this grant

When is the application deadline?
The application deadline is January 7, 2028.
How much funding can an applicant receive?
The largest award listed is $500,000, and total program funding is also listed at $500,000.
Who can apply for this grant?
Eligible applicants include public and private institutions of higher education, small businesses, other for-profit organizations, nonprofits with or without 501(c)(3) status, state, county, city, and special district governments, public housing authorities, independent school districts, and federally recognized tribal governments and tribal organizations. Foreign entities are not eligible, and non-domestic components of U.S. organizations are also ineligible.
Can a sole proprietor or single-member LLC apply?
The facts do not say. The eligibility list names small businesses and for-profit organizations generally, but it does not specifically address sole proprietors or single-member LLCs, so check the full notice before assuming you qualify.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible applicants.

Summary

NIH/NCI R01 research grants for projects integrating imaging and liquid biopsy tumor monitoring during cancer therapy to assess therapy response and resistance. Eligible applicants include universities, hospitals/nonprofits, small businesses, for-profit organizations, and state, local, and tribal governments; foreign entities are ineligible.

About this grant

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

Related grants

Open opportunities funding similar work, from the same funder or in the same place.

All grantsGrants by stateGrants by industry