OpenFederal grantOpen to for-profit businessesPAR-25-136

Laboratories to Optimize Digital Health (R01 Clinical Trial Required)

National Institutes of HealthCloses Jan 7, 2028(451 days left)

Does this fit your business?

This is an NIH research grant for building digital health test beds to refine and clinically test digital mental health interventions, with clinical trials required. It fits healthcare, technology, and research organizations that can run statistically powered trials; retail, finance, and housing businesses with nothing pointing to digital mental health research should not bother. The award amount is not published.

Best for
Healthcare and biotech organizations running clinical research on digital mental health tools, Technology and software teams with established digital health platforms, Universities and research institutions with clinical trial capability, Small businesses developing evidence-based digital health interventions
Not for
Retail, finance, or housing businesses with no digital health research component, Organizations unable to run clinical trials, Applicants seeking funding for general operations or non-research purposes
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (health, clinical)
89
Strong Match
Technology & SoftwareMatches your industry (digital)
79
Strong Match
Energy & Clean TechMatches your industry (efficiency)
76
Strong Match
Agriculture & FarmingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Construction & InfrastructureLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Education & TrainingLimit: Nothing in this notice points to education & training
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match
Transportation & LogisticsLimit: Not clearly about your industry or what you need funding for; check the…
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research, R&D
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
January 7, 2028.
Who can apply for this grant?
Small businesses, for-profit organizations, nonprofits, public and private institutions of higher education, state, local, and tribal governments, public housing authorities, independent school districts, and certain other entities including foreign organizations and faith-based or community-based organizations can apply.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are listed as eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify.
Can a nonprofit apply?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (other than institutions of higher education) are both listed as eligible.

Summary

NIH/NIMH R01 grants for research projects that develop digital health test beds to refine, optimize, and clinically test digital mental health interventions. Eligible applicants include small businesses, for-profit organizations, nonprofits, universities, state/local/tribal governments, and others; clinical trials required.

About this grant

NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and quality of digital mental health interventions. This NOFO is intended to support the development of digital health test beds that leverage well-established digital mental health platforms,to rapidly refine and optimize existing evidence-based digital health interventions and conduct clinical trials testing digital mental health interventions that are statistically powered to provide a definitive answer regarding the intervention's effectiveness.

Who can apply

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Topics and uses of funds

Topics

  • Health
  • Technology
  • Science

Program contact

National Institutes of Healthgrantsinfo@nih.gov301-402-2541

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