OpenFederal grantOpen to for-profit businessesRFA-HL-27-004

Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

National Institutes of HealthCloses Nov 7, 2028(756 days left)Up to $85,000

Does this fit your business?

This is an NIH small research grant (R03) for current or recently completed NHLBI K01/K08/K23/K25 awardees who need pilot data to move toward an independent R01 application. If you or your organization do not sponsor one of these specific K awardees, do not bother applying; the eligibility gate is the K award, not your industry. Foreign entities are excluded.

Best for
Current or recently completed NHLBI K01, K08, K23, or K25 awardees, Eligible organizations sponsoring a K awardee, US-based research institutions
Not for
Businesses with no NHLBI K-award connection, Foreign organizations or non-US components, Organizations without a K awardee to sponsor
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
86
Strong Match
Technology & SoftwareMatches your industry (tech)
78
Strong Match
Education & TrainingMatches your industry (stem)
70
Good Match
Transportation & LogisticsMatches your industry (transit)
70
Good Match
Agriculture & FarmingLimit: Nothing in this notice points to agriculture & farming
54
Possible Match
Arts & CultureLimit: Nothing in this notice points to arts & culture
54
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Construction & InfrastructureLimit: Nothing in this notice points to construction & infrastructure
54
Possible Match
Energy & Clean TechLimit: Nothing in this notice points to energy & clean tech
54
Possible Match
Environment & ConservationLimit: Nothing in this notice points to environment & conservation
54
Possible Match
Finance & BankingLimit: Nothing in this notice points to finance & banking
54
Possible Match
Food & BeverageLimit: Nothing in this notice points to food & beverage
54
Possible Match
Housing & Real EstateLimit: Nothing in this notice points to housing & real estate
54
Possible Match
ManufacturingLimit: Nothing in this notice points to manufacturing
54
Possible Match
Retail & E-CommerceLimit: Nothing in this notice points to retail & e-commerce
54
Possible Match
Social Services & NonprofitLimit: Nothing in this notice points to social services & nonprofit
54
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility), Individuals
Award range
Up to $85,000

Questions about this grant

When is the application deadline?
The application deadline is 2028-11-07.
How much funding can an applicant receive?
The largest award is $85,000, with total program funding of $3,900,000 and about 29 awards expected.
Who can apply for this grant?
Only current or recently completed NHLBI K01, K08, K23, and K25 awardees, sponsored by an eligible organization, can apply. Current K awardees may apply starting in the third year of their K award project period; recently completed awardees are eligible if the earliest potential R03 award start date is within two years of the end of their K award project period. Foreign organizations and foreign components are not eligible.
Can a sole proprietor or single-member LLC apply?
The facts do not specifically address sole proprietors or single-member LLCs. Small businesses are listed among eligible applicant types, but the core requirement is that the applicant must be an eligible organization sponsoring an NHLBI K01/K08/K23/K25 awardee.
Can a nonprofit apply?
Yes. Nonprofits with and without 501(c)(3) status (other than institutions of higher education) are listed among eligible applicant types, though the applicant must be sponsoring an NHLBI K awardee.

Summary

Small grants (R03) for current or recently completed NHLBI K01/K08/K23/K25 awardees to expand their K-award research or start a new study, generating preliminary data toward an R01 application. Applicants must be eligible organizations sponsoring the K awardee; foreign entities are excluded.

About this grant

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees. Current NHLBI K01, K08, K23, and K25 awardees may apply for this R03 support starting in the third year of their K award Project Period. Recently completed NHLBI K01, K08, K23, and K25 award recipients are eligible to apply or resubmit A1 applications if the earliest potential R03 award start date is within two years of the end of their K award Project Period.The R03 grant mechanism supports research projects that can be completed within two years and with limited resources. These projects are expected to generate preliminary data to bolster a subsequent R01-equivalent application. Eligible projects include, but are not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or creation of novel experimental model systems.Applicants are required to maintain a minimum of 40% protected research effort during the R03 award period. This requirement can be fulfilled through a combination of effort on the proposed R03 project and other research projects, irrespective of funding source.For current and former K23 awardees, the research proposed in the R03 application may or may not include patient-oriented research.

Who can apply

Only the following NHLBI K01, K08, K23, and K25 awardees are eligible to apply for this funding opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Topics and uses of funds

Topics

  • Health
  • Science
  • Research

Program contact

National Institutes of HealthNHLBI_R03@nih.gov301-402-2541

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