OpenFederal grantOpen to for-profit businessesPA-27-061

NIH Research Program Projects (Parent P01 Clinical Trial Optional)

National Institutes of HealthCloses May 25, 2029(953 days left)

Does this fit your business?

This is an NIH Program Project (P01) grant for multidisciplinary biomedical research programs with a common scientific theme, requiring at least two research projects and an administrative core. It suits research-driven organizations in healthcare and biotech whose work aligns with a participating NIH institute's mission. Businesses without in-house research capability or a biomedical focus should not bother applying.

Best for
Biomedical research teams at universities and nonprofits, Small businesses and for-profits running multidisciplinary health research programs, Organizations whose work aligns with a participating NIH institute's mission
Not for
Businesses with no biomedical research capability, Organizations without the capacity to run multiple coordinated research projects
Estimated fit by industry, best first
IndustryEstimated fit
Healthcare & BiotechMatches your industry (clinical)
68
Good Match
Environment & ConservationLimit: Closes in 7 days
54
Possible Match
Technology & SoftwareLimit: Closes in 7 days
54
Possible Match
Energy & Clean TechLimit: Closes in 7 days
53
Possible Match
Arts & CultureLimit: Closes in 7 days
51
Possible Match
Education & TrainingLimit: Closes in 7 days
49
Possible Match
Show all 15 industries
Estimated fit by industry, best first
IndustryEstimated fit
Social Services & NonprofitLimit: Closes in 7 days
49
Possible Match
Agriculture & FarmingLimit: Closes in 7 days
48
Possible Match
Housing & Real EstateLimit: Closes in 7 days
48
Possible Match
ManufacturingLimit: Closes in 7 days
46
Possible Match
Food & BeverageLimit: Closes in 7 days
45
Possible Match
Finance & BankingLimit: Closes in 7 days
44
Possible Match
Construction & InfrastructureLimit: Closes in 7 days
43
Possible Match
Retail & E-CommerceLimit: Closes in 7 days
43
Possible Match
Transportation & LogisticsLimit: Closes in 7 days
40
Possible Match

These are our matcher’s estimates for a typical business in each industry. A real match depends on your size, your state and what you need the money for — check your own fit.

What this funds

Money can be used for
Research
Who can apply
Small businesses, For-profit companies, Nonprofits, State and local governments, Tribal governments and organizations, Colleges and universities, Other applicants (see eligibility)

Questions about this grant

When is the application deadline?
September 25, 2026.
Who can apply for this grant?
Small businesses, for-profit organizations, nonprofits with or without 501(c)(3) status, public and private institutions of higher education, independent school districts, state, county, city and special district governments, public housing and Indian housing authorities, federally recognized tribal governments and tribal organizations, and other eligible groups including faith-based, community-based, regional, federal agencies, U.S. territories, and foreign institutions. The program must fit the scientific mission of a participating NIH institute.
Can a sole proprietor or single-member LLC apply?
The facts do not say. Small businesses are listed as eligible, but the notice does not specify whether sole proprietors or single-member LLCs qualify, so check with NIH directly.
Can a nonprofit apply?
Yes. Both nonprofits with 501(c)(3) status and nonprofits without it (other than institutions of higher education) are listed as eligible applicants.

Summary

NIH Program Project (P01) grants fund multidisciplinary biomedical research programs with a common scientific theme, requiring at least two research projects and an administrative core. Eligible applicants include small businesses, for-profits, nonprofits, universities, state/local/tribal governments, and other organizations aligned with participating NIH institute missions.

About this grant

Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) invite applications for the investigator-initiated Program Project (P01). A P01 supports a broadly based, multidisciplinary research program with a specific major scientific objective or theme. The proposed Program Projects are focused on the programmatic interests of one or more of the participating ICOs based on their scientific missions. A program project utilizes research projects with a common central scientific theme, an administrative core, and optional shared resource core(s) to accomplish ICOs' programmatic objectives.

Who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Topics and uses of funds

Topics

  • Health
  • Science

Program contact

National Institutes of HealthEmail: ncirefof@dea.nci.nih.gov301-402-2541

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